Scientific Advisors

Ginger Constantine, MD
Ginger initiated EndoRheum Consultants, an organization dedicated to assisting companies with all clinical aspects of drug development, in 2010. Prior to EndoRheum, she was associated with Wyeth Pharmaceuticals as both a Rheumatology Consultant and later as part of their Medical Affairs group. Dr. Constantine assumed responsibility for the Wyeth Women’s Health and Bone Repair Therapeutic areas, guiding her staff to the completion of numerous INDS and more than 10 NDAs and European dossiers in the areas of contraception, osteoporosis, menopausal symptoms, endometriosis, and osteoarthritis. Ginger received her medical degree from Temple University and has authored more than 100 articles, posters and abstracts.


Benjamin Cravatt, Ph.D.
Dr. Cravatt is currently a Professor and Chair of the Department of Chemical Physiology and co-director of the Center for Physiological Proteomics at the Scripps Research Institute. He earned his B.S. in biological sciences and a B.A. in history from Stanford University and his Ph.D. in macromolecular and cellular structure and chemistry from The Scripps Research Institute. His research has won a number of awards, including a Top 100 Young Innovator award from Technology Review, a Promega Young Life Scientist Award from the American Society for Cell Biology and the Eli Lilly Ward in Biological Chemistry from the American Chemical Society.


Andrea Dunaif, MD
Andrea is the Charles F Kettering Professor of Endocrinology & Metabolism & Vice-Chair for Research at Northwestern University, Feinberg School of Medicine, with a research focus on PCOS. Previously, she was Director of Women’s Health at Harvard’s Brigham and Women’s Hospital. Andrea has received numerous awards and honors, including the Endocrine Society’s highest award for clinical research, the Clinical Investigator Award, and the Arnold Adolph Berthold Medal Prize from the German Endocrine Society. Dr. Dunaif is a past president of the Endocrine Society, a former associate editor of The Journal of Clinical Endocrinology and Metabolism and Obesity and a past Chair of the National Institutes of Health Integrative and Clinical Endocrinology and Reproduction Study Section.


David A. Ehrmann, MD
David is a Professor of Medicine, Associate Director of Chicago Clinical Research Center and Director of the University of Chicago Center for PCOS. He specializes in the diagnosis and treatment of PCOS and T2 diabetes. Dr. Ehrmann has written more than 60 medical publications, including book chapters, articles, and abstracts. He has served on numerous national committees and on the editorial boards of the Journal of Clinical Endocrinology and Metabolism and the American Journal of Physiology.


John Kozarich, Ph.D.
Dr. Kozarich is currently Chairman and President of ActivX, a biopharmaceutical company that discovers and develops highly selective, best in class, small molecules for major unmet medical needs. Previously, Dr. Kozarich served as Vice President at Merck Research Laboratories, where he had primary responsibility for a number of collaborations with companies, including Aurora Biosciences, Cubist and KaroBio. He also held faculty positions at the University of Maryland and Yale University School of Medicine. Dr. Kozarich also served as Vice President, R&D at Alkermes. He has over 125 primary scientific publications and holds several patents. Dr. Kozarich is internationally known for his work on enzyme mechanisms and received the Pfizer Award in Enzyme Chemistry from the American Chemical Society.


Richard Legro, MD
Richard is a Professor of Obstetrics and Gynecology and Co-Leader, Participant and Clinical Interactive Resources at the Penn State Clinical and Translational Institute. He specializes in women’s health, PCOS, and reproductive endocrinology. Dr. Legro has authored over 100 publications, many in the area of PCOS. He received his medical degree from the Mount Sinai School of Medicine.


Enrique Saez, PhD
Enrique is an Associate Professor in the Department of Physiology at Scripps University. His research is focused on the regulation of energy balance in mammals through genetic modulation of energy storage and the activation of novel nutrient signaling pathways that involve nuclear receptors. Prior to joining Scripps, Enrique studied the molecular genetics of hormone action and the role of nuclear receptors in metabolic disease at the Genomics Institute of the Novartis Research Foundation. He earned his PhD in genetics at Harvard University under Dr. Bruce Spiegelman.


Paul Schimmel, Ph.D.
Dr. Schimmel is the Ernest and Jean Hahn Professor at the Skaggs Institute for Chemical Biology at the Scripps Research Institute. He was previously a Professor of Biochemistry and Biophysics in the Department of Biology at MIT. Dr. Schimmel is co-author of more than 450 publications and a textbook on biophysical chemistry, is the holder of several patents and is a member of the American Academy of Arts and Sciences, the National Academy of Sciences, the American Philosophical Society, and the Institute of Medicine. Dr. Schimmel is a co-founder or co-founding director of several biotechnology companies, including Alkermes, Alnylam Pharmaceuticals, Sirtris Pharmaceuticals, Cubist Pharmaceuticals, Momenta Pharmaceuticals and Repligen.


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